NIH-funded research NIH-funded research

Online support for people with differentiated thyroid cancer after radioactive iodine treatment

Official title: The development of a technology-based information support intervention (iSupport) among patients with differentiated thyroid cancer post radioactive iodine therapy

Funded at Georgetown University · NIH-11311315 · Data updated 2026-11-12

A web-based program to help people with differentiated thyroid cancer manage side effects and improve quality of life after radioactive iodine treatment.

More Thyroid Cancer research and trials

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionGeorgetown University
NIH-funded
Lab location1 site (Washington, United States)
Project startMarch 2, 2023
Project endFebruary 29, 2028
Funding year2026
Award (this year)$248,999
NIH project number5R00CA277588-04
Project IDNIH-11311315 on NIH RePORTER

Who could benefit from this research

Could help

People diagnosed with differentiated thyroid cancer who have completed radioactive iodine therapy and can access an online program are the ideal candidates.

Less likely to help

People who have not received RAI, who cannot use web-based tools, or who require immediate medical care for complications may not benefit from this intervention.

What this research studies

You would use a web-based program called RAI Support that provides education, symptom-management tools, and emotional support after radioactive iodine (RAI) therapy. The research team will run a small randomized trial with about 88 participants where some people use RAI Support and others receive usual care. The study will check whether people find the program usable and acceptable and whether it helps quality of life, symptom burden, knowledge, confidence in managing symptoms, and cancer-related distress. The project is led by researchers at Georgetown University and runs through 2028.

Why it matters

Potential benefit: If successful, this program could reduce symptom burden and improve quality of life for thyroid cancer survivors after RAI.

How similar studies have gone: Web-based survivorship and symptom-management programs have helped other cancer survivor groups, but applying this approach specifically to thyroid cancer after RAI is relatively new.

Where this research is happening

  • Georgetown University
    Washington, United States
    Active

Researchers

  • Principal investigator: Carr, Alaina L — Georgetown University
  • Study coordinator: Carr, Alaina L

Related research

Other NIH-funded projects on the same topics.

  • A web-based support tool for patients with thyroid cancer after treatment

    This study is testing a helpful online tool called iSupport for people with differentiated thyroid cancer who have had radioactive iodine treatment, to provide them with useful information and support to make their recovery easier and improve their quality of life.

    NIH research Georgetown University · Washington, United States · NIH-11231962

  • WTC Dust and Thyroid Cancer Progression in Human Organoids

    This grant tests how World Trade Center dust might influence thyroid cancer progression using human thyroid organoids to model real-life exposure.

    NIH research Icahn School of Medicine at Mount Sinai · New York, United States · NIH-11578742

  • Integrating molecular signals to guide thyroid cancer care

    A doctor-scientist team at Brigham and Women’s Hospital is studying how tumor biology and the immune environment can guide personalized monitoring and treatment for differentiated thyroid cancer.

    NIH research Brigham and Women's Hospital · Boston, United States · NIH-11452026

  • Metabolic Imaging to Track Treatment Response in Aggressive Thyroid Cancer

    This grant explores a new way to watch how aggressive thyroid cancers respond to treatment using a special MRI technique that tracks tumor metabolism.

    NIH research University of Tx Md Anderson Can Ctr · Houston, United States · NIH-11420949

  • Adoptive T-cell Therapy for Anaplastic Thyroid Cancer

    A patient-focused program explores using patient immune cells engineered to target and fight anaplastic thyroid cancer, especially for those whose cancer has stopped responding to standard treatments.

    NIH research University of Tx Md Anderson Can Ctr · Houston, United States · NIH-11420948

  • Overcoming Resistance to BRAF Inhibitors in Aggressive Thyroid Cancers

    A patient-focused research effort to find new ways to treat difficult thyroid cancers that no longer respond to current BRAF inhibitors.

    NIH research University of Tx Md Anderson Can Ctr · Houston, United States · NIH-11420947

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.