NIH-funded research R01 grant

Online guided family treatment for teens with anorexia nervosa

Official title: Confirming the Effectiveness and Efficiency of Online Guided Self-Help Family-Based Treatment for Adolescent Anorexia Nervosa

Funded at Stanford University · NIH-11139593 · Data updated 2026-11-12

An online guided self-help family program designed to help teenagers with anorexia nervosa regain healthy weight and eating attitudes while using less therapist time than standard family therapy.

More Anorexia Nervosa research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionStanford University
NIH-funded
Lab location1 site (Stanford, United States)
Project startSeptember 20, 2022
Project endJuly 31, 2027
Funding year2025
Award (this year)$534,963
NIH project number5R01MH130388-04
Project IDNIH-11139593 on NIH RePORTER

Who could benefit from this research

Could help

Adolescents diagnosed with anorexia nervosa and their families who are appropriate for family-based treatment and able to participate in online sessions are the ideal candidates.

Less likely to help

Teens with severe medical instability, those for whom family-based approaches are inappropriate, or families unable to use online tools may not benefit from this program.

What this research studies

If your teen has anorexia, this project compares an online guided family-based program that families use with brief coach support to the usual family-based therapy delivered by therapists. Families follow structured online lessons and meet briefly with a trained guide while researchers track weight, eating-related thoughts, and recovery over time. The trial is randomized and runs at multiple clinical sites to see how the online approach works in real-world care, building on earlier pilot work. If confirmed, the online option could make effective treatment easier to find and use for more families.

Why it matters

Potential benefit: If successful, this approach could expand access to effective family-based treatment and allow more teens to get timely care by reducing required therapist time.

How similar studies have gone: Earlier pilot studies and a multisite randomized feasibility trial found similar improvements in weight and eating cognitions with guided self-help family treatment while using about 75% less therapist time.

Where this research is happening

  • Stanford University
    Stanford, United States
    Active

Researchers

  • Principal investigator: Lock, James D — Stanford University
  • Study coordinator: Lock, James D

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.