One smart arm cuff that measures blood pressure, heart pumping strength, and blood flow

Smart Cuff: Multi-Parameter Hemodynamic Monitoring via a Single Convenient Device

NIH-funded research University of Pittsburgh at Pittsburgh · NIH-11263684

A new smart arm cuff will measure blood pressure, how strongly the heart pumps, and blood flow for people having surgery or in intensive care.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Pittsburgh at Pittsburgh NIH-funded
Lab location1 site (Pittsburgh, United States)
Project IDNIH-11263684 on NIH RePORTER

What this research studies

You would wear an arm cuff that records the detailed pressure waveform each time it inflates and deflates. The team will record those cuff waveforms at the same time as standard clinical monitors so they can train smart algorithms to compute blood pressure, cardiac output, and ejection fraction from the cuff signal. The device will actively control cuff pressure and run the algorithms in real time. Finally, the smart cuff's readings will be compared to reliable reference monitors in patients to confirm accuracy.

Who could benefit from this research

Good fit: Adults undergoing surgery or receiving intensive care monitoring where detailed blood pressure and cardiac function measurements are needed are the intended candidates.

Not a fit: People not hospitalized (outpatients), children, or patients whose arm anatomy or severe arrhythmias prevent reliable cuff measurements may not benefit from this device.

Why it matters

Potential benefit: If successful, a single noninvasive cuff could let clinicians monitor multiple key heart and blood flow measures more conveniently and quickly, helping detect and treat low blood pressure or shock sooner.

How similar studies have performed: Pulse-wave and cuff-based algorithms have shown promise for blood pressure and some cardiac output estimates, but using a cuff to estimate ejection fraction in patients is largely novel and less proven.

Where this research is happening

Pittsburgh, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.