NIH-funded research NIH-funded research

One Health monitoring of rickettsial pathogens in wildlife, ticks, and fleas in Northwestern California

Official title: A One Health Approach to Surveillance of Pathogenic and Emerging Rickettsia in Mammals, Ticks, and Fleas of Northwestern California

Funded at Humboldt State University · NIH-11424694 · Data updated 2026-11-12

A field study will monitor rickettsia bacteria in small mammals and their ticks and fleas in Northwestern California to understand how these infections spread and affect people.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionHumboldt State University
NIH-funded
Lab location1 site (Arcata, United States)
Project startSeptember 9, 2026
Project endAugust 31, 2030
Funding year2026
Award (this year)$145,000
NIH project number1R16AI201228-01
Project IDNIH-11424694 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates would be rural or suburban residents in northwestern California who might be exposed to ticks or fleas and who are interested in how environmental factors influence infection risk.

Less likely to help

Individuals not exposed to tick- or flea-borne pathogens or not in the study regions may see limited direct benefit.

What this research studies

This project will collect animals and ectoparasites from California to detect and map several Rickettsia species using real-time PCR, nested PCR, and sequencing. Researchers will identify which host species and vectors carry the bacteria and how this relates to human exposure risk. The findings aim to reveal transmission cycles in wild animals, guiding future public health surveillance and prevention efforts. The study focuses on ecological relationships rather than individual medical treatment.

Why it matters

Potential benefit: If successful, the work could improve early warning of human rickettsial infections and inform public health strategies to reduce exposure.

How similar studies have gone: Previous ecological surveillance has helped map vector-borne pathogen risks, supporting the potential value of this approach in California.

Where this research is happening

  • Humboldt State University
    Arcata, United States
    Active

Researchers

  • Principal investigator: Zhong, Jianmin — Humboldt State University
  • Study coordinator: Zhong, Jianmin

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.