NIH-funded research U01 cooperative agreement

One Health approach to understand how people catch liver fluke and how to control it

Official title: One-Health Approach to Study Human Fasciola hepatica Transmission and Inform Strategic Control

Funded at University of Texas Med Br Galveston · NIH-11538019 · Data updated 2026-11-12

A health project using a One Health approach to study human fascioliasis transmission in two Peruvian highland sites and related animals and environment to guide prevention.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionUniversity of Texas Med Br Galveston
NIH-funded
Lab location1 site (Galveston, United States)
Project startApril 22, 2022
Project endMarch 31, 2027
Funding year2026
Award (this year)$251,011
NIH project number3U01AI168622-05S1
Project IDNIH-11538019 on NIH RePORTER

Who could benefit from this research

Could help

Individuals living in affected areas, families with children in the study sites, and livestock keepers in those communities.

Less likely to help

People outside the study sites or those not exposed to fascioliasis may not benefit directly.

What this research studies

This project will look at how fascioliasis spreads among people, livestock, snails, and the environment in the Peruvian highlands. Researchers will collect data on human infections, animal health, snail hosts, and environmental factors over time to build a fuller picture of risk. The study combines field observations with models to identify moments when interventions could prevent infections and livestock losses. Results could help communities reduce disease and improve animal health and farm productivity.

Why it matters

Potential benefit: Could lead to better prevention strategies for people and livestock, reducing illness and economic losses.

How similar studies have gone: Previous work shows that One Health approaches can reveal transmission drivers across humans, animals, and the environment, though this specific multi-site approach is novel.

Where this research is happening

  • University of Texas Med Br Galveston
    Galveston, United States
    Active

Researchers

  • Principal investigator: Cabada, Miguel Mauricio — University of Texas Med Br Galveston
  • Study coordinator: Cabada, Miguel Mauricio

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.