Omalizumab for COPD with Allergies

Clinical trial of omalizumab for allergen sensitized and exposed individuals with COPD

NIH-funded research Johns Hopkins University · NIH-11170528

This project is testing if a medication called omalizumab can help people with COPD who also have allergies to common indoor triggers.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionJohns Hopkins University NIH-funded
Lab location1 site (Baltimore, United States)
Project IDNIH-11170528 on NIH RePORTER

What this research studies

COPD affects everyone differently, and doctors are looking for ways to tailor treatments to each person. We know that many people with COPD also have allergies, and this combination might lead to worse health problems. This project will give omalizumab, a medicine already used for allergic asthma, to people with COPD who are allergic to common indoor allergens and exposed to them. We hope to see if this targeted approach can improve their health.

Who could benefit from this research

Good fit: Ideal candidates are adults aged 21 and older with COPD who have known allergies to common indoor allergens and are exposed to them.

Not a fit: Patients with COPD who do not have allergic sensitization or exposure to indoor allergens may not receive benefit from this specific treatment approach.

Why it matters

Potential benefit: If successful, this could offer a new, personalized treatment option for people with COPD who also experience allergies, potentially reducing their risk of severe health issues.

How similar studies have performed: Omalizumab has shown significant benefit for individuals with allergic asthma who have similar allergic sensitization and exposure, suggesting a promising approach for COPD.

Where this research is happening

Baltimore, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Allergic Disease
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.