Offering HIV prevention pills to people in TB-affected households
TB PrEP - Integrating HIV prevention with TB household contact evaluation
This project brings HIV prevention pills (PrEP) to people who live with someone diagnosed with tuberculosis to help stop new HIV infections.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Washington NIH-funded |
| Lab location | 1 site (Seattle, United States) |
| Project ID | NIH-11187190 on NIH RePORTER |
What this research studies
If someone in your home has tuberculosis, health workers will visit to check household members for TB and offer HIV testing and PrEP to those who are HIV-negative. The team will adapt a proven PrEP delivery approach so it can be offered during routine TB household visits and link people to local clinics for follow-up. They will monitor who accepts PrEP, how well people stay on it, and whether this approach reaches more at-risk people than current practices. The work focuses on communities in Uganda with high TB and HIV rates.
Who could benefit from this research
Good fit: Ideal participants are HIV-negative adolescents and adults who live in the same household as someone recently diagnosed with TB in a high HIV-burden area (e.g., Uganda) and who are eligible for PrEP.
Not a fit: People who are already living with HIV, not eligible for PrEP, or who do not live in TB-affected households are unlikely to benefit from this program.
Why it matters
Potential benefit: If successful, this could make it much easier for people in TB-affected homes to start PrEP and reduce new HIV infections.
How similar studies have performed: Household-based PrEP delivery and programs for serodifferent couples have shown feasibility and benefit in high-burden settings, but offering PrEP specifically through TB contact investigations is a newer approach.
Where this research is happening
Seattle, United States
- University of Washington — Seattle, United States (Active)
Researchers
- Principal investigator: Ross, Jennifer M — University of Washington
- Study coordinator: Ross, Jennifer M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.