Nurse-delivered therapy for homebound patients with serious illness

A Pragmatic Randomized Control Trial of Nurse-Delivered Brief Meaning Centered Psychotherapy for Homebound Palliative Care Patients

NIH-funded research Sloan-Kettering Inst Can Research · NIH-10478931

This study is looking at how a special type of therapy called Meaning Centered Psychotherapy, provided by nurses, can help homebound adults with advanced cancer feel better emotionally and improve their quality of life, especially when they’re dealing with feelings of anxiety and sadness.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionSloan-Kettering Inst Can Research NIH-funded
Lab location1 site (New York, United States)
Project IDNIH-10478931 on NIH RePORTER

What this research studies

This research investigates the effectiveness of a brief therapy called Meaning Centered Psychotherapy, delivered by nurses, for homebound adults suffering from advanced cancer. The focus is on addressing existential distress, anxiety, and depression that often accompany serious illnesses, particularly in patients who are unable to engage in social activities. By utilizing a mixed methods approach, including a pilot randomized control trial, the study aims to evaluate how this intervention can improve emotional well-being and quality of life for these vulnerable patients. The research is designed to be practical and applicable in home settings, ensuring that care can be delivered where patients feel most comfortable.

Who could benefit from this research

Good fit: Ideal candidates for this research are homebound adults aged 21 and older who are living with advanced cancer and experiencing anxiety or depression.

Not a fit: Patients who are not homebound or those without serious illness may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly improve the emotional well-being and quality of life for homebound patients facing serious illnesses.

How similar studies have performed: Previous research has shown promising results for similar psychosocial interventions in improving mental health outcomes for patients with serious illnesses.

Where this research is happening

New York, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.