Northwestern Alzheimer's Research Participant Program

Clinical Core

NIH-funded research Northwestern University · NIH-11169785

A program that follows and collects brain scans, tests, and samples from older adults with and without memory problems to support Alzheimer's research.

Quick facts

Grant typeP30 center grant
Study typeNIH-funded research
Funding institutionNorthwestern University NIH-funded
Lab location1 site (Chicago, United States)
Project IDNIH-11169785 on NIH RePORTER

What this research studies

You would join a group of about 500 volunteers who are seen yearly for memory testing, neuroimaging, and collection of blood and other biospecimens, with an option to donate brain tissue. The program focuses on early and pre-symptomatic stages of Alzheimer’s, studies people with unusually preserved memory (“SuperAgers”), and includes non-amnestic dementias like primary progressive aphasia to learn why brains age differently. Data and samples are shared with researchers and used to support prevention trials and other studies. Participation typically involves annual clinic visits, imaging, cognitive testing, and optional tissue donation.

Who could benefit from this research

Good fit: Ideal candidates are older adults with or without memory concerns who can attend yearly visits, agree to cognitive testing and brain imaging, and are willing to provide biospecimens or consider tissue donation.

Not a fit: People seeking immediate clinical treatment benefits or those unable or unwilling to travel for in-person visits, imaging, or biospecimen donation may not receive direct benefit from participating.

Why it matters

Potential benefit: If successful, this program could speed discovery of earlier detection methods and better ways to prevent or treat Alzheimer's by providing well-characterized participants and shared data.

How similar studies have performed: Large cohort efforts like ADNI and other Alzheimer's Disease Research Centers have successfully identified biomarkers and supported trials, so this builds on proven approaches.

Where this research is happening

Chicago, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Alzheimer disease dementiaAlzheimer syndromeAlzheimer's DiseaseAlzheimer's disease and related dementia
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.