Northwest Genomics Center supporting the All of Us genome program
Northwest Genomics Center for All of Us
This project will produce genetic and whole-genome data and return medically important genetic and drug-response results to All of Us participants.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Washington NIH-funded |
| Lab location | 1 site (Seattle, United States) |
| Project ID | NIH-11379446 on NIH RePORTER |
What this research studies
If you are an All of Us participant, the Northwest Genomics Center will generate high-quality genotyping and whole genome sequence data from participant samples and add advanced long-read sequencing and other -omic data. The team will review and classify genetic variants using clinical standards and return medically actionable and pharmacogenomic results to participants who request them. Sequencing and interpretation are performed in CLIA-compliant labs by experienced genomic clinicians and scientists. The center plans to process large numbers of samples each year and share de-identified data with the All of Us Data Research Center to support further research.
Who could benefit from this research
Good fit: People enrolled in the All of Us Research Program who consent to genomic testing and to receive genomic return-of-results are the ideal candidates.
Not a fit: People who are not enrolled in All of Us, who do not opt to receive genomic results, or whose genetic changes are not clinically actionable may not receive direct benefit.
Why it matters
Potential benefit: Participants could receive clinically important genetic findings and pharmacogenomic information that may inform medical care or medication choices.
How similar studies have performed: Similar genomics programs have successfully returned actionable findings to participants, and the NWGC has already delivered tens of thousands of genotypes and genomes and returned thousands of results.
Where this research is happening
Seattle, United States
- University of Washington — Seattle, United States (Active)
Researchers
- Principal investigator: Jarvik, Gail Pairitz — University of Washington
- Study coordinator: Jarvik, Gail Pairitz
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.