Noninvasive imaging to assess kidney transplant health
Noninvasive assessment of renal fibrosis in kidney transplant recipients bymulti-contrast magnetic resonance imaging
This study is testing a new MRI method to help doctors check for kidney scarring in people who have had a kidney transplant, so they can monitor kidney health without needing to do any painful biopsies.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Hugo W. Moser Res Inst Kennedy Krieger NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-11054751 on NIH RePORTER |
What this research studies
This research focuses on developing a new magnetic resonance imaging (MRI) technique to noninvasively assess renal fibrosis in kidney transplant recipients. By combining diffusion-weighted imaging with magnetization transfer contrast, the study aims to enhance the detection of fibrosis without the need for invasive kidney biopsies. The approach also includes analyzing blood flow and microstructural integrity within the kidney, which could provide a comprehensive view of transplant health. This method could lead to better monitoring of kidney function over time, ultimately improving patient care.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who have received a kidney transplant and are at risk for chronic allograft dysfunction.
Not a fit: Patients who have not undergone kidney transplantation or those with acute kidney issues unrelated to transplant may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide a safer and more effective way to monitor kidney transplant health, potentially reducing the need for invasive procedures.
How similar studies have performed: Other research has shown promise in using advanced MRI techniques for assessing organ health, suggesting that this approach could be effective.
Where this research is happening
Baltimore, United States
- Hugo W. Moser Res Inst Kennedy Krieger — Baltimore, United States (Active)
Researchers
- Principal investigator: Stabinska, Julia — Hugo W. Moser Res Inst Kennedy Krieger
- Study coordinator: Stabinska, Julia
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.