Noninvasive evaluation of liver pressure and health using advanced imaging techniques

Noninvasive assessment of portal hypertension and hepatic interstitial pressure with advanced magnetic resonance elastography

NIH-funded research Mayo Clinic Rochester · NIH-11059159

This study is testing a new, painless way to check liver health and pressure using advanced imaging technology, which could help people with chronic liver disease get better and safer care without needing invasive procedures.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionMayo Clinic Rochester NIH-funded
Lab location1 site (Rochester, United States)
Project IDNIH-11059159 on NIH RePORTER

What this research studies

This research focuses on developing a noninvasive method to assess portal hypertension and liver health using advanced magnetic resonance elastography (MRE). By utilizing a new 3D imaging technique, the study aims to provide a safer and more accessible alternative to the invasive procedures currently used to measure liver pressure. Patients with chronic liver disease will benefit from this innovative approach, which seeks to improve diagnosis and monitoring without the need for skilled operators. The research will systematically evaluate various liver parameters to enhance understanding of liver conditions.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with chronic liver disease, particularly those at risk for portal hypertension.

Not a fit: Patients with non-liver related health issues or those without chronic liver disease may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to earlier and more accurate diagnosis of liver conditions, ultimately improving patient outcomes.

How similar studies have performed: Previous studies have shown promise in using magnetic resonance elastography for liver assessment, indicating that this approach may lead to significant advancements in noninvasive diagnostics.

Where this research is happening

Rochester, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions alcohol induced hepatic injuryalcohol induced liver disorderalcohol induced liver injuryalcohol related liver diseasealcohol-associated liver disease
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.