Non-invasive vein-wave monitoring for people with heart failure
Non-Invasive Venous Waveform Analysis (NIVA) in patients with Heart Failure (HF)
This project uses a small sensor and software that reads vein pulse patterns through the skin to monitor fluid levels in people with heart failure.
Quick facts
| Grant type | Sbir 2 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Volumetrix, LLC NIH-funded |
| Lab location | 1 site (Nashville, United States) |
| Project ID | NIH-11248913 on NIH RePORTER |
What this research studies
Researchers are using a non-invasive device that records venous waveforms through the skin and applies a proprietary algorithm to estimate intravascular fluid status. The team will conduct interface and usability tests with patients and clinicians to refine the device and software for everyday clinical use. This Phase IIB work builds on early human and animal proof-of-concept data and aims to prepare the device for wider clinical deployment and commercialization. The emphasis is on making the tool reliable and easy to use in real healthcare settings.
Who could benefit from this research
Good fit: Adults with heart failure who experience volume overload or recurrent hospitalizations for congestion are the most likely candidates.
Not a fit: People without heart failure, those with skin problems or severe limb swelling that block external readings, or patients who require immediate invasive hemodynamic monitoring may not benefit.
Why it matters
Potential benefit: If successful, this could give people with heart failure a simple, non-invasive way to track fluid status and help prevent hospitalizations from congestion.
How similar studies have performed: Early proof-of-concept human and animal studies indicate NIVA can reflect intravascular volume, but larger usability and clinical outcome studies are still needed.
Where this research is happening
Nashville, United States
- Volumetrix, LLC — Nashville, United States (Active)
Researchers
- Principal investigator: Hocking, Kyle Mitchell — Volumetrix, LLC
- Study coordinator: Hocking, Kyle Mitchell
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.