Non-invasive ultrasound surgery for brain tumors
Official title: Ultra-high precision image-guided incisionless transcranial ultrasound surgery
Funded at Univ of North Carolina Chapel Hill · NIH-11173875 · Data updated 2026-11-12
This study is testing a new way to use ultrasound during brain surgery to remove tumors more accurately, which could help patients with glioblastoma multiforme have better outcomes and a quicker recovery.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Univ of North Carolina Chapel Hill NIH-funded |
| Lab location | 1 site (Chapel Hill, United States) |
| Project start | August 20, 2024 |
| Project end | April 30, 2028 |
| Funding year | 2025 |
| Award (this year) | $750,055 |
| NIH project number | 5R01EB036295-02 |
| Project ID | NIH-11173875 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients diagnosed with glioblastoma multiforme or other complex brain tumors requiring surgical intervention.
✕Less likely to help
Patients with non-surgical brain conditions or those whose tumors are not amenable to surgical resection may not benefit from this research.
What this research studies
This research focuses on developing ultra-high precision image-guided ultrasound surgery to treat brain tumors, particularly glioblastoma multiforme. By utilizing advanced imaging techniques, the goal is to enhance the accuracy of tumor resections while preserving healthy brain tissue. The approach aims to overcome current limitations in surgical precision, which is critical for successful outcomes in complex brain surgeries. Patients may benefit from a less invasive procedure that could lead to improved survival rates and quality of life.
Why it matters
Potential benefit: If successful, this research could provide patients with a safer and more effective treatment option for brain tumors, potentially improving survival rates.
How similar studies have gone: Previous research has shown promise in using advanced imaging and non-invasive techniques for tumor treatment, indicating potential for success in this novel approach.
Where this research is happening
-
Univ of North Carolina Chapel Hill
Chapel Hill, United States Active
Researchers
- Principal investigator: Pinton, Gianmarco — Univ of North Carolina Chapel Hill
- Study coordinator: Pinton, Gianmarco
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.