Non-invasive treatment for early-stage breast cancer using focused ultrasound
Official title: Validation and translation of a non-invasive, MR-guided breast cancer therapy
Funded at University of Utah · NIH-10855746 · Data updated 2026-11-12
This study is testing a new, gentle treatment for early-stage localized breast cancer that uses focused ultrasound to target the cancer while keeping an eye on it with special imaging, making it safer and more effective for patients.
Quick facts
| Grant type | R37 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Utah NIH-funded |
| Lab location | 1 site (Salt Lake City, United States) |
| Project start | February 1, 2023 |
| Project end | January 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $506,060 |
| NIH project number | 5R37CA224141-07 |
| Project ID | NIH-10855746 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with early-stage, localized breast cancer who are seeking non-invasive treatment options.
✕Less likely to help
Patients with advanced breast cancer or those requiring more aggressive treatment methods may not benefit from this research.
What this research studies
This research focuses on developing a non-invasive therapy for early-stage localized breast cancer using a specialized magnetic resonance-guided focused ultrasound (MRgFUS) system. The approach involves delivering focused energy deep within the breast tissue while monitoring the treatment in real-time with high-resolution imaging. The study aims to refine treatment planning techniques and validate methods for monitoring temperature changes in tissues during the procedure. By integrating these advancements into a clinic-ready software environment, the research seeks to enhance the effectiveness and safety of breast cancer treatment.
Why it matters
Potential benefit: If successful, this research could provide a less invasive treatment option for patients with localized breast cancer, potentially reducing recovery time and improving quality of life.
How similar studies have gone: Previous research has shown promising results with similar non-invasive techniques, indicating potential for success in this novel application.
Where this research is happening
-
University of Utah
Salt Lake City, United States Active
Researchers
- Principal investigator: Payne, Allison — University of Utah
- Study coordinator: Payne, Allison
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.