Non-invasive treatment for early-stage breast cancer using focused ultrasound

Validation and translation of a non-invasive, MR-guided breast cancer therapy

NIH-funded research University of Utah · NIH-10855746

This study is testing a new, gentle treatment for early-stage localized breast cancer that uses focused ultrasound to target the cancer while keeping an eye on it with special imaging, making it safer and more effective for patients.

Quick facts

Grant typeR37 grant
Study typeNIH-funded research
Funding institutionUniversity of Utah NIH-funded
Lab location1 site (Salt Lake City, United States)
Project IDNIH-10855746 on NIH RePORTER

What this research studies

This research focuses on developing a non-invasive therapy for early-stage localized breast cancer using a specialized magnetic resonance-guided focused ultrasound (MRgFUS) system. The approach involves delivering focused energy deep within the breast tissue while monitoring the treatment in real-time with high-resolution imaging. The study aims to refine treatment planning techniques and validate methods for monitoring temperature changes in tissues during the procedure. By integrating these advancements into a clinic-ready software environment, the research seeks to enhance the effectiveness and safety of breast cancer treatment.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with early-stage, localized breast cancer who are seeking non-invasive treatment options.

Not a fit: Patients with advanced breast cancer or those requiring more aggressive treatment methods may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could provide a less invasive treatment option for patients with localized breast cancer, potentially reducing recovery time and improving quality of life.

How similar studies have performed: Previous research has shown promising results with similar non-invasive techniques, indicating potential for success in this novel application.

Where this research is happening

Salt Lake City, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.