Non-invasive screening for brain blood flow issues in children with Down syndrome.
Non-invasive biometric screening for cerebrovascular disorders in persons with Down syndrome.
This study is looking at how to spot blood flow problems in the brains of children with Down syndrome using safe and simple methods, like checking blood pressure and taking special pictures of the brain, to help catch any issues early and protect their health.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Children's Hospital of Los Angeles NIH-funded |
| Lab location | 1 site (Los Angeles, United States) |
| Project ID | NIH-11054555 on NIH RePORTER |
What this research studies
This research investigates how to identify cerebrovascular disorders in children with Down syndrome using non-invasive biometric methods. The approach includes measuring blood pressure and utilizing advanced imaging techniques to assess brain blood flow. By focusing on early detection, the study aims to prevent irreversible neurological damage associated with cerebrovascular accidents. The research is led by Dr. Jonathan Santoro, who is receiving training in data analysis and clinical trials to enhance the study's effectiveness.
Who could benefit from this research
Good fit: Ideal candidates for this research are children with Down syndrome, particularly those under the age of 11.
Not a fit: Patients without Down syndrome or those over the age of 11 may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to early detection and prevention of serious brain conditions in children with Down syndrome.
How similar studies have performed: Previous research has shown promise in using non-invasive methods for screening cerebrovascular disorders, making this approach both innovative and grounded in prior success.
Where this research is happening
Los Angeles, United States
- Children's Hospital of Los Angeles — Los Angeles, United States (Active)
Researchers
- Principal investigator: Santoro, Jonathan Douglas — Children's Hospital of Los Angeles
- Study coordinator: Santoro, Jonathan Douglas
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.