Non-invasive electrical nerve block to reduce muscle spasticity
Transcutaneous Direct Current Motor Nerve Block for Spasticity
This study is exploring a new way to help people with muscle tightness, like those with cerebral palsy, stroke, or spinal cord injuries, by using a gentle electrical technique that can reduce unwanted nerve signals and improve movement.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Case Western Reserve University NIH-funded |
| Lab location | 1 site (Cleveland, United States) |
| Project ID | NIH-10814406 on NIH RePORTER |
What this research studies
This research investigates a novel approach to alleviate muscle spasticity using a non-invasive electrical nerve block technique. By applying direct current through the skin, the study aims to interrupt unwanted nerve impulses that contribute to increased muscle tone and associated disabilities. The methodology involves developing and testing specialized surface electrodes to ensure effective delivery of the electrical stimulation. Patients with conditions like cerebral palsy, stroke, or spinal cord injury may benefit from this innovative treatment that promises rapid, reversible, and gradable effects.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with spasticity due to conditions such as cerebral palsy, stroke, or spinal cord injury.
Not a fit: Patients with spasticity not caused by neurological conditions or those who do not respond to electrical stimulation may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide a new, effective treatment option for patients suffering from debilitating muscle spasticity.
How similar studies have performed: Previous research has shown promise in using electrical nerve blocks for similar conditions, indicating potential for success in this innovative approach.
Where this research is happening
Cleveland, United States
- Case Western Reserve University — Cleveland, United States (Active)
Researchers
- Principal investigator: Vrabec, Tina Louise — Case Western Reserve University
- Study coordinator: Vrabec, Tina Louise
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.