NIH-funded research R01 grant

Nighttime lighting to lower falls in people with Alzheimer's and related dementias

Official title: A Pragmatic Crossover Trial to Test the Effectiveness of a Novel Lighting System to Reduce Nighttime Falls in Persons with Alzheimer’s Disease and Related Dementias

Funded at Univ of North Carolina Chapel Hill · NIH-11144500 · Data updated 2026-11-12

This project uses a new nighttime lighting system to help people with Alzheimer's disease and related dementias get up at night with fewer falls.

More s Disease research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniv of North Carolina Chapel Hill
NIH-funded
Lab location1 site (Chapel Hill, United States)
Project startJuly 1, 2022
Project endJune 30, 2027
Funding year2025
Award (this year)$1,197,027
NIH project number5R01AG075010-04
Project IDNIH-11144500 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates are ambulatory adults aged 65 or older with Alzheimer's disease or related dementias who live in assisted-living settings and sometimes get up at night.

Less likely to help

People who are non-ambulatory, who do not wake at night, who live entirely at home with no assisted-living component, or who have very poor vision may not receive benefit.

What this research studies

You would remain in your assisted-living community while the study compares nights with a passive, balance-promoting lighting system versus usual lighting. Each participant experiences both lighting conditions in a randomized crossover design so researchers can compare fall rates within the same person. The lights are designed to turn on in a way that supports posture and walking without requiring you to change your behavior. The team builds on an earlier small trial that showed a 34% drop in falls and will track falls, injuries, and related healthcare use.

Why it matters

Potential benefit: If successful, this could cut nighttime falls and reduce related injuries and hospital stays for people with dementia.

How similar studies have gone: A prior NIH R21 randomized crossover trial by the same team reported a 34% reduction in falls, indicating promising preliminary results.

Where this research is happening

  • Univ of North Carolina Chapel Hill
    Chapel Hill, United States
    Active

Researchers

  • Principal investigator: Zimmerman, Sheryl — Univ of North Carolina Chapel Hill
  • Study coordinator: Zimmerman, Sheryl

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.