Nicotine information and how different tobacco products affect priority populations

Communicating about Nicotine and Differential Risks of Tobacco Products in Priority Populations

NIH-funded research Georgia State University · NIH-11262877

This project uses clear messages together with very low nicotine cigarettes to help smokers—especially people with mental health conditions or low income—understand risks and reduce smoking.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionGeorgia State University NIH-funded
Lab location1 site (Atlanta, United States)
Project IDNIH-11262877 on NIH RePORTER

What this research studies

If you smoke and are in a priority group, researchers will provide targeted messages about very low nicotine cigarettes (VLNCs) and offer opportunities to use these products under controlled conditions. The team combines previous clinical trials of VLNCs with new communication experiments so you will see real messages while using the product rather than only answering hypothetical questions. They will track changes in beliefs, smoking behavior, and related outcomes over time. Findings will be used to shape public-facing messages and policy implementation that aim to protect communities with higher tobacco-related harm.

Who could benefit from this research

Good fit: Ideal candidates are adult cigarette smokers in priority populations—such as people with mental health conditions or low socioeconomic status—who are willing to receive messages and try very low nicotine cigarettes under study conditions.

Not a fit: People who do not smoke, only use e-cigarettes, or are unwilling to try very low nicotine products are unlikely to benefit directly from participating.

Why it matters

Potential benefit: If successful, this work could lead to clearer public messages and policies that help smokers understand nicotine and reduce smoking-related harm.

How similar studies have performed: Previous randomized trials showed VLNCs can reduce dependence and cigarettes smoked per day, but combining these trials with actual messaging and behavioral measurement is a newer and less-tested approach.

Where this research is happening

Atlanta, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions DiseaseDisorder
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.