Next-generation Chagas Detect Plus Rapid Test for Sensitive and Specific Diagnosis
Official title: Development of Next-gen Chagas DetectTM Plus Rapid test for sensitive and specific diagnosis of Chagas disease
Funded at Inbios International, INC. · NIH-11332759 · Data updated 2026-11-12
A new rapid test for Chagas disease aims to deliver fast, highly accurate results so people who might be infected can get timely care.
Quick facts
| Grant type | Sbir 2 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Inbios International, INC. NIH-funded |
| Lab location | 1 site (Seattle, UNITED STATES) |
| Project start | May 8, 2024 |
| Project end | April 30, 2027 |
| Funding year | 2026 |
| Award (this year) | $974,356 |
| NIH project number | 5R44AI184032-03 |
| Project ID | NIH-11332759 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates are individuals at risk for Chagas disease or with suspected infection, including those in endemic regions or with exposure through blood transfusion, organ transplantation, or congenital transmission.
✕Less likely to help
Patients without suspected Chagas infection or those in settings where the test is not yet FDA-cleared/CLIA-waived may not benefit.
What this research studies
This project focuses on improving a rapid diagnostic test for Chagas disease to achieve very high sensitivity and specificity. It involves optimizing a prototype test (CDPv2) and planning the steps needed for FDA clearance and CLIA waiver so it can be used in the US and globally. If successful, the test could enable earlier treatment and reduce transmission, especially in endemic and immigrant communities.
Why it matters
Potential benefit: If successful, the test could allow quick and reliable diagnosis at the point of care, leading to earlier treatment and reduced transmission.
How similar studies have gone: Previous generations of CDP tests achieved strong performance, and this project aims to match or surpass that performance with a streamlined regulatory pathway.
Where this research is happening
-
Inbios International, INC.
Seattle, United States Active
Researchers
- Principal investigator: Raychaudhuri, Syamal X — Inbios International, INC.
- Study coordinator: Raychaudhuri, Syamal X
Related research
Other NIH-funded projects on the same topics.
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Sensitive point-of-care test for tick-borne spotted fever group rickettsioses
A fast, easy-to-use test kit is being developed to detect early signs of tick-borne spotted fever group infections so patients can get treated sooner.
-
Creating a quick at-home test for prostate cancer detection using fingerstick blood samples
This study is working on a quick and easy at-home test that helps African-American men check for high levels of a protein linked to prostate cancer using just a drop of blood from a fingerstick, making it simple to use without any fancy equipment.
-
Creating a new rapid test for diagnosing Chagas disease
This study is working on a new, quick test called Chagas Detect PlusTM to help find Chagas disease in people who might not show any symptoms, so they can get treated sooner and avoid serious health issues later on.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.