New zinc-based materials for heart stents in children
Novel Zinc-Nanocomposite Materials for Pediatric Bioresorbable Cardiovascular Stents
This study is working on new stents made from special materials that can safely dissolve in kids' bodies after helping with heart problems, so they can grow without any extra devices getting in the way.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California Los Angeles NIH-funded |
| Lab location | 1 site (Los Angeles, United States) |
| Project ID | NIH-10450158 on NIH RePORTER |
What this research studies
This research focuses on developing innovative bioresorbable stents made from zinc nanocomposite materials specifically designed for pediatric patients with congenital heart disease. The approach aims to create stents that can safely dissolve in the body after serving their purpose, allowing for natural growth and development of the child's cardiovascular system. By utilizing zinc, which is biocompatible and has favorable mechanical properties, the research seeks to overcome the limitations of current stent options that are unsuitable for growing children. The methodology includes testing the mechanical strength and corrosion rates of these new materials to ensure they can withstand the pressures of the aorta and pulmonary arteries.
Who could benefit from this research
Good fit: Ideal candidates for this research are pediatric patients diagnosed with congenital heart defects, particularly those experiencing aortic coarctation or pulmonary artery obstructions.
Not a fit: Patients who do not have congenital heart defects or those who are not in need of vascular interventions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide safer and more effective treatment options for children with severe vascular obstructions, reducing the need for more invasive surgeries.
How similar studies have performed: Previous research has shown promise in using bioabsorbable metals for stents, but this specific approach using zinc nanocomposites is relatively novel.
Where this research is happening
Los Angeles, United States
- University of California Los Angeles — Los Angeles, United States (Active)
Researchers
- Principal investigator: Linsley, Chase — University of California Los Angeles
- Study coordinator: Linsley, Chase
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.