New Ways to Protect Organs During Sepsis
Novel Approaches to Maintaining Organ Function in Sepsis
This research looks for new ways to stop organ damage in patients suffering from sepsis, a life-threatening response to infection.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Feinstein Institute for Medical Research NIH-funded |
| Lab location | 1 site (Manhasset, United States) |
| Project ID | NIH-11129760 on NIH RePORTER |
What this research studies
Sepsis is a severe condition affecting millions of Americans each year, often leading to death because there are no effective treatments. This project explores how certain immune cells, called neutrophils, become overly active and cause inflammation and tissue damage in organs like the lungs during sepsis. Researchers have found a new type of neutrophil, called APANs, that might make organ injury worse. Understanding these cells could lead to new ways to protect vital organs.
Who could benefit from this research
Good fit: This foundational research is relevant for anyone who has experienced or is at risk of developing sepsis and its associated organ complications.
Not a fit: Patients without sepsis or related acute lung injuries would not directly benefit from this specific research.
Why it matters
Potential benefit: If successful, this work could lead to new therapies that reduce organ damage and improve survival rates for patients with sepsis.
How similar studies have performed: While previous work has advanced understanding of neutrophil activation in sepsis, this project explores a newly discovered neutrophil population, making its approach novel.
Where this research is happening
Manhasset, United States
- Feinstein Institute for Medical Research — Manhasset, United States (Active)
Researchers
- Principal investigator: Wang, Ping — Feinstein Institute for Medical Research
- Study coordinator: Wang, Ping
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.