New ways to measure memory decline in Alzheimer's disease
Novel Story Recall Measures as Indicators of Cognitive Decline Associated with Alzheimer's Disease and Related Disorders Biomarkers: A Collaborative Study of Existing Data
This study is looking at how small changes in memory, like remembering names and the order of a story, can help spot early signs of Alzheimer's disease, so we can find ways to keep track of brain health and explore new treatments.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Wisconsin-Madison NIH-funded |
| Lab location | 1 site (Madison, United States) |
| Project ID | NIH-11009917 on NIH RePORTER |
What this research studies
This research investigates how subtle changes in memory can indicate early cognitive decline associated with Alzheimer's disease (AD) and related disorders. By analyzing existing data from multiple long-term studies, researchers aim to develop innovative measures that assess memory performance through a story recall task. The study focuses on specific aspects of memory, such as how well individuals can recall names and the order of information, which may correlate with biological markers of AD. This approach could help identify cognitive decline earlier and improve monitoring for potential treatments.
Who could benefit from this research
Good fit: Ideal candidates for this research include adults over 21 who may be experiencing early signs of cognitive decline or are at risk for Alzheimer's disease.
Not a fit: Patients with advanced Alzheimer's disease or those who do not exhibit any cognitive decline may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to earlier detection of cognitive decline in patients, allowing for timely interventions.
How similar studies have performed: Previous research has shown promise in using cognitive measures to detect early signs of Alzheimer's, making this approach both innovative and grounded in existing findings.
Where this research is happening
Madison, United States
- University of Wisconsin-Madison — Madison, United States (Active)
Researchers
- Principal investigator: Mueller, Kimberly D — University of Wisconsin-Madison
- Study coordinator: Mueller, Kimberly D
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.