New ways to improve health and quality of life for patients receiving stem cell transplants
Novel Intervention Approaches to Alleviate Allogeneic Transplant-Related Morbidity and Mortality
This study is looking to find the best way to help older patients with blood cancers feel better and live healthier lives after they receive a special type of stem cell transplant, by comparing different types of care they might receive.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Fred Hutchinson Cancer Center NIH-funded |
| Lab location | 1 site (Seattle, United States) |
| Project ID | NIH-10770557 on NIH RePORTER |
What this research studies
This research focuses on improving the health-related quality of life for older and medically vulnerable patients undergoing allogeneic hematopoietic cell transplantation (HCT) for hematological malignancies. It aims to compare different approaches, including supportive care, palliative care, and targeted clinical management, to see which method best enhances patient outcomes after transplantation. Patients will be randomly assigned to one of these interventions or to standard care, allowing researchers to evaluate their effectiveness in reducing morbidity and mortality. The study will also assess survival rates and resource utilization associated with each approach.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults or medically infirm patients diagnosed with hematological malignancies who are considering or have been recommended for allogeneic HCT.
Not a fit: Patients who are younger and otherwise healthy may not benefit as much from this research, as the focus is on vulnerable populations.
Why it matters
Potential benefit: If successful, this research could significantly enhance the quality of life and survival rates for vulnerable patients undergoing stem cell transplants.
How similar studies have performed: Previous research has shown promising results in improving patient outcomes through targeted interventions in similar populations, indicating that this approach has potential for success.
Where this research is happening
Seattle, United States
- Fred Hutchinson Cancer Center — Seattle, United States (Active)
Researchers
- Principal investigator: Sorror, Mohamed — Fred Hutchinson Cancer Center
- Study coordinator: Sorror, Mohamed
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.