New ways to fight antibiotic-resistant infections
Innovative Strategies to Combat Antibiotic-resistant Infections
['FUNDING_OTHER'] · WASHINGTON UNIVERSITY · NIH-11042746
This study is exploring new ways to treat tough urinary tract infections caused by bacteria that don't respond to regular antibiotics, aiming to create treatments that work better and help reduce the need for traditional antibiotics.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | WASHINGTON UNIVERSITY (nih funded) |
| Locations | 1 site (SAINT LOUIS, UNITED STATES) |
| Trial ID | NIH-11042746 on ClinicalTrials.gov |
What this research studies
This research focuses on developing innovative treatments for antibiotic-resistant bacterial infections, particularly targeting multi-drug resistant strains that cause urinary tract infections. By utilizing findings from basic science, the project aims to create antibiotic-sparing medicines that can effectively treat these infections while reducing the reliance on traditional antibiotics. The approach includes neutralizing bacterial adhesins that facilitate infection, thereby preventing bacteria from colonizing the host. This could lead to more effective management of infections that are currently difficult to treat.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals experiencing recurrent urinary tract infections or those infected with multi-drug resistant bacteria.
Not a fit: Patients with infections caused by antibiotic-sensitive bacteria may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide new treatment options for patients suffering from antibiotic-resistant infections, improving their health outcomes.
How similar studies have performed: Other research has shown promise in developing treatments targeting antibiotic-resistant infections, indicating that this approach has potential for success.
Where this research is happening
SAINT LOUIS, UNITED STATES
- WASHINGTON UNIVERSITY — SAINT LOUIS, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: HULTGREN, SCOTT J. — WASHINGTON UNIVERSITY
- Study coordinator: HULTGREN, SCOTT J.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.