New ways to deliver drugs for treating breast cancer that has spread to the brain
Novel drug delivery strategies for treatment of breast cancer brain metastases
This study is looking for better ways to deliver cancer treatments to women with breast cancer that has spread to the brain, especially for those with tougher types like triple negative and HER2-positive, to help improve their treatment outcomes.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Baltimore VA Medical Center NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-10881721 on NIH RePORTER |
What this research studies
This research focuses on developing innovative drug delivery methods specifically for women with breast cancer that has metastasized to the brain. It addresses the unique challenges posed by the blood-brain barrier and other obstacles that limit the effectiveness of current treatments. By exploring new strategies to enhance drug penetration and reduce resistance, the research aims to improve outcomes for patients with aggressive forms of breast cancer, such as triple negative and HER2-positive types. The study is particularly relevant for active duty and Veteran women diagnosed with breast cancer.
Who could benefit from this research
Good fit: Ideal candidates for this research are women diagnosed with triple negative or HER2-positive breast cancer who have developed brain metastases.
Not a fit: Patients with early-stage breast cancer or those without brain metastases may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly improve survival rates and quality of life for patients with breast cancer brain metastases.
How similar studies have performed: While there have been advancements in drug delivery systems, this approach is exploring novel strategies specifically targeting breast cancer brain metastases, making it a potentially groundbreaking area of research.
Where this research is happening
Baltimore, United States
- Baltimore VA Medical Center — Baltimore, United States (Active)
Researchers
- Principal investigator: Kim, Anthony J. — Baltimore VA Medical Center
- Study coordinator: Kim, Anthony J.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.