New Ways to Deliver Cancer-Fighting Viruses for Pancreatic Cancer
Advancing Systematic Delivery of Oncolytic Adenovirus for Pancreatic Cancer
This project is developing a new way to deliver cancer-fighting viruses to treat pancreatic cancer and help doctors see where the cancer is.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Minnesota NIH-funded |
| Lab location | 1 site (Minneapolis, United States) |
| Project ID | NIH-11098760 on NIH RePORTER |
What this research studies
Pancreatic cancer is a very serious disease with few good treatment options. This project is working on a new type of virus, called an oncolytic adenovirus, that can both find and destroy pancreatic cancer cells. These special viruses are designed to carry a "tag" that allows doctors to see the cancer using imaging scans and also deliver radiation directly to the tumor. The goal is to make it easier to deliver these viruses throughout the body and improve how we detect and treat this aggressive cancer.
Who could benefit from this research
Good fit: Patients with pancreatic ductal adenocarcinoma (PDAC) who are seeking new and advanced treatment options might be ideal candidates for future clinical applications of this research.
Not a fit: Patients with other types of cancer or those not suitable for viral therapies may not directly benefit from this specific treatment approach.
Why it matters
Potential benefit: If successful, this approach could lead to more effective and targeted treatments for pancreatic cancer, potentially improving outcomes for patients.
How similar studies have performed: While oncolytic viruses have shown promise in other cancer types, this specific combination of systemic delivery, imaging, and radiotherapy for pancreatic cancer is a novel and preclinical approach.
Where this research is happening
Minneapolis, United States
- University of Minnesota — Minneapolis, United States (Active)
Researchers
- Principal investigator: Davydova, Julia — University of Minnesota
- Study coordinator: Davydova, Julia
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.