New ways to build complex molecules using organoboron chemistry
Official title: New Strategies in Catalytic Organic Synthesis with Organoboron Reagents
Funded at Boston College · NIH-11528806 · Data updated 2026-11-12
This grant supports developing user-friendly chemical reactions that let researchers make important molecules from readily available starting materials.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Boston College NIH-funded |
| Lab location | 1 site (Chestnut Hill, United States) |
| Project start | May 1, 2018 |
| Project end | April 30, 2028 |
| Funding year | 2026 |
| Award (this year) | $34,066 |
| NIH project number | 3R35GM127140-09S1 |
| Project ID | NIH-11528806 on NIH RePORTER |
Who could benefit from this research
✓Could help
No direct patient participation is required for this basic chemistry grant.
✕Less likely to help
Patients are not currently enrolled; the research is foundational chemistry.
What this research studies
Researchers at Boston College are advancing catalytic methods that transform simple building blocks into more complex compounds, focusing on stereoselective steps that control shape and arrangement. The work aims to create practical, scalable processes that don’t require highly specialized equipment. If successful, these methods could streamline the synthesis of medicines and other useful chemicals. The project will build on prior successes in diboration, cross-coupling, and boronate rearrangements to broaden access to new transformations.
Why it matters
Potential benefit: Potentially faster, cheaper routes to important medicines and materials for patients.
How similar studies have gone: Previous work in catalytic boronate chemistry has shown promising, scalable transformations, suggesting potential for wider adoption.
Where this research is happening
-
Boston College
Chestnut Hill, United States Active
Researchers
- Principal investigator: Morken, James Patrick — Boston College
- Study coordinator: Morken, James Patrick
Related research
Other NIH-funded projects on the same topics.
-
New boron-nitrogen chemistry to expand medicines and biology
A Boston College team is developing new boron-nitrogen-based chemical space to create innovative molecules and tools for biology and drug discovery.
-
mHealth dashboard to support family mental health in Rwanda and beyond
A smartphone-based dashboard helps deliver a proven family-based mental health program in Rwanda, making it easier to keep families engaged and ensure high-quality care.
-
Digital dashboard to support family mental health in Rwanda
A digital dashboard is being developed and tested to help deliver a proven family-based mental-health program in Rwanda and share lessons that could help families in the US.
-
How war affects children's mental health across generations and how families can help
The team is looking at how parents' experiences of war in Sierra Leone influence their children's emotions and behavior to guide family-focused support.
-
Preventing tuberculosis in rural South Africa using clinic systems improvements
A clinic-based systems approach aims to improve tuberculosis prevention, diagnosis, and treatment for people in rural South Africa, especially household contacts and those living with HIV.
-
Improving TB care and prevention in rural South Africa
This project will use a clinic-level systems approach to strengthen TB screening, treatment, and prevention for people in rural South Africa, especially household contacts and people living with HIV.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.