New ways to block cancer growth in colorectal cancer
Novel Mechanisms of Inhibiting Transcriptional Coactivators for Anti-Cancer Therapy in Colorectal Cancer
This study is looking at how specific proteins help colorectal cancer cells, especially those with K-Ras mutations, grow and survive, with the goal of finding new ways to slow down or stop the cancer, which could lead to better treatments for patients.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Nebraska Medical Center NIH-funded |
| Lab location | 1 site (Omaha, United States) |
| Project ID | NIH-10986969 on NIH RePORTER |
What this research studies
This research investigates how certain proteins, known as transcriptional co-activators, contribute to the growth of colorectal cancer cells, particularly those with K-Ras mutations. The team aims to understand the interactions between these proteins and other cellular components that promote cancer cell survival. By identifying key binding partners and their roles, the researchers hope to develop strategies to inhibit these interactions, potentially leading to new treatments for colorectal cancer. Patients may benefit from therapies that target these mechanisms to slow or stop tumor growth.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients diagnosed with colorectal cancer, especially those with K-Ras mutations.
Not a fit: Patients with colorectal cancer who do not have K-Ras mutations may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to innovative therapies that effectively inhibit the growth of colorectal cancer.
How similar studies have performed: Other research has shown promise in targeting transcriptional co-activators in cancer therapy, suggesting that this approach could be effective.
Where this research is happening
Omaha, United States
- University of Nebraska Medical Center — Omaha, United States (Active)
Researchers
- Principal investigator: Fisher, Kurt — University of Nebraska Medical Center
- Study coordinator: Fisher, Kurt
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.