New treatments to improve heart healing after a heart attack
Official title: Novel Inhibitors for Temporal Modulation of T-Lymphocytes during Chronic Heart Failure
Funded at Pennsylvania State Univ Hershey Med Ctr · NIH-10878724 · Data updated 2026-11-12
This study is looking at how certain immune cells in your body can help your heart heal after a heart attack, with the goal of finding better ways to support recovery and improve heart function.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Pennsylvania State Univ Hershey Med Ctr NIH-funded |
| Lab location | 1 site (Hershey, United States) |
| Project start | July 1, 2023 |
| Project end | June 30, 2027 |
| Funding year | 2024 |
| Award (this year) | $587,161 |
| NIH project number | 5R01HL167912-03 |
| Project ID | NIH-10878724 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals who have experienced a heart attack and are at risk of developing chronic heart failure.
✕Less likely to help
Patients who have not had a heart attack or those with advanced heart failure may not benefit from this research.
What this research studies
This research investigates how immune responses, particularly T-lymphocytes, affect heart healing after a heart attack. It focuses on understanding the timing and mechanisms of these immune responses to find ways to modulate them for better recovery. By studying the changes in T-cells during the transition from acute heart attack to chronic heart failure, the researchers aim to identify specific targets for therapy that could improve heart function. The approach includes using animal models to explore the effects of manipulating these immune cells on heart healing.
Why it matters
Potential benefit: If successful, this research could lead to new therapies that enhance heart recovery and function after a heart attack.
How similar studies have gone: Previous research has shown promising results in manipulating immune responses to improve heart healing, indicating that this approach has potential for success.
Where this research is happening
-
Pennsylvania State Univ Hershey Med Ctr
Hershey, United States Active
Researchers
- Principal investigator: Bansal, Shyam Sunder — Pennsylvania State Univ Hershey Med Ctr
- Study coordinator: Bansal, Shyam Sunder
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.