New treatments for patients with chronic lymphocytic leukemia

Paradigm Shift in the Management of Patients with Previously Untreated Chronic Lymphocytic Leukemia through NCI-sponsored Clinical Trials

NIH-funded research Mayo Clinic Rochester · NIH-10942547

This study is looking for newly diagnosed patients with chronic lymphocytic leukemia (CLL) to try out new combinations of treatments, like Venetoclax and Ibrutinib, to see how well they work, so you can get access to the latest therapies and help improve care for others in the future.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionMayo Clinic Rochester NIH-funded
Lab location1 site (Rochester, United States)
Project IDNIH-10942547 on NIH RePORTER

What this research studies

This research focuses on improving the management of chronic lymphocytic leukemia (CLL) in patients, particularly those who are newly diagnosed. The approach involves conducting clinical trials to evaluate the effectiveness of combining different therapies, such as Venetoclax and Ibrutinib, in older patients. By participating in these trials, patients may receive cutting-edge treatments that are not yet widely available. The research aims to gather data on treatment outcomes and biomarkers to enhance future care for CLL patients.

Who could benefit from this research

Good fit: Ideal candidates for this research are patients aged 65 and older who have been newly diagnosed with chronic lymphocytic leukemia.

Not a fit: Patients who have previously received treatment for chronic lymphocytic leukemia may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective treatment options for patients with chronic lymphocytic leukemia, potentially improving survival rates and quality of life.

How similar studies have performed: Previous clinical trials have shown promising results with similar treatment combinations for chronic lymphocytic leukemia, indicating a potential for success in this research.

Where this research is happening

Rochester, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.