New treatments for pancreatitis using ubiquitin pathway modulators
Ubiquitin pathway modulators for treating pancreatitis
['FUNDING_SBIR_1'] · PROGENRA, INC. · NIH-10824472
This study is looking at new ways to help people with acute and chronic pancreatitis by finding treatments that support healthy cell function, and it aims to test new compounds to see how well they work in improving this condition.
Quick facts
| Phase | ['FUNDING_SBIR_1'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | PROGENRA, INC. (nih funded) |
| Locations | 1 site (MALVERN, UNITED STATES) |
| Trial ID | NIH-10824472 on ClinicalTrials.gov |
What this research studies
This research focuses on developing new treatments for acute and chronic pancreatitis by promoting mitochondrial health. The approach involves activating the ubiquitin proteasome system, which plays a crucial role in clearing damaged mitochondria. Researchers will evaluate novel compounds for their effectiveness in cellular and animal models of pancreatitis, aiming to understand their mechanisms of action. The ultimate goal is to create small molecule drugs that can effectively treat this condition.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals suffering from acute or chronic pancreatitis.
Not a fit: Patients with pancreatitis caused by non-biological factors or those who do not respond to existing treatments may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to innovative therapies that significantly improve the management of pancreatitis.
How similar studies have performed: Previous research has shown promise in using similar approaches to enhance mitochondrial health and treat related conditions, indicating potential for success in this area.
Where this research is happening
MALVERN, UNITED STATES
- PROGENRA, INC. — MALVERN, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: SURESH, KUMAR — PROGENRA, INC.
- Study coordinator: SURESH, KUMAR
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.