New treatments for opioid addiction and overdose
Novel Therapeutics for Opioid Use Disorder in the Acute Overdose and Maintenance Settings
This study is looking for new medications to help people with opioid use disorder by making it easier to reverse overdoses and reduce withdrawal symptoms, so they can feel better and stay safe.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Epiodyne, INC. NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project ID | NIH-10705309 on NIH RePORTER |
What this research studies
This research focuses on developing innovative medications to improve the treatment of opioid use disorder (OUD) and enhance overdose reversal. It aims to create new mu-opioid receptor antagonists and partial agonists that can effectively counteract the effects of opioid overdoses while minimizing withdrawal symptoms. The approach involves testing these novel compounds to determine their efficacy and safety in both acute overdose situations and long-term maintenance therapy for individuals struggling with opioid dependence.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with opioid use disorder or those who have experienced an opioid overdose.
Not a fit: Patients who are not dependent on opioids or who do not have a history of opioid overdose may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and safer treatments for individuals suffering from opioid addiction and those at risk of overdose.
How similar studies have performed: Previous research has shown promise in developing new treatments for opioid addiction, but this approach is considered novel and aims to address significant gaps in current therapies.
Where this research is happening
San Francisco, United States
- Epiodyne, INC. — San Francisco, United States (Active)
Researchers
- Principal investigator: Gehlert, Donald R — Epiodyne, INC.
- Study coordinator: Gehlert, Donald R
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.