New treatments for opioid addiction
Official title: Novel Therapeutics for Treating Opioid Use Disorder
Funded at Virginia Commonwealth University · NIH-11071519 · Data updated 2026-11-12
This study is looking at a new way to help people with Opioid Use Disorder by testing a drug called Nor-Levo-α-acetylmethadol (nor-LAAM) to see if it can provide better and safer treatment options than what’s currently available.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Virginia Commonwealth University NIH-funded |
| Lab location | 1 site (Richmond, United States) |
| Project start | June 10, 2025 |
| Project end | June 9, 2027 |
| Funding year | 2025 |
| Award (this year) | $48,974 |
| NIH project number | 1F31DA060668-01A1 |
| Project ID | NIH-11071519 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with Opioid Use Disorder who are seeking alternative treatment options.
✕Less likely to help
Patients who are not struggling with opioid addiction or those who have contraindications to the study medications may not benefit from this research.
What this research studies
This research focuses on developing innovative therapies for Opioid Use Disorder (OUD), a serious condition affecting many individuals. The project aims to explore the potential of Nor-Levo-α-acetylmethadol (nor-LAAM), a metabolite of an existing drug, to improve treatment outcomes. By optimizing drug delivery methods, the research seeks to enhance the effectiveness of therapies while minimizing side effects, such as cardiovascular risks associated with current treatments. Patients may benefit from a more effective and safer alternative to existing OUD medications.
Why it matters
Potential benefit: If successful, this research could provide patients with more effective and safer treatment options for opioid addiction.
How similar studies have gone: Previous research has shown promise in using similar approaches to improve treatment for opioid addiction, indicating potential for success in this area.
Where this research is happening
-
Virginia Commonwealth University
Richmond, United States Active
Researchers
- Principal investigator: Ingabire, Diane — Virginia Commonwealth University
- Study coordinator: Ingabire, Diane
Related research
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.