New treatments for Non-Hodgkin lymphoma linked to Epstein-Barr virus
Therapy for Non-Hodgkin lympoma
This study is looking at how the Epstein-Barr virus might be linked to certain types of Non-Hodgkin lymphoma in people with HIV, with the goal of finding new ways to treat these tough-to-treat cancers and help patients feel better.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Univ of North Carolina Chapel Hill NIH-funded |
| Lab location | 1 site (Chapel Hill, United States) |
| Project ID | NIH-11020542 on NIH RePORTER |
What this research studies
This research investigates the connection between Epstein-Barr virus (EBV) and various types of Non-Hodgkin lymphoma (NHL), particularly in patients with HIV. The team aims to understand how EBV contributes to the development and persistence of these aggressive lymphomas, which are often resistant to current treatments. By exploring the biology of these cancers, the researchers hope to identify new therapeutic strategies that could improve outcomes for affected patients. The study will involve analyzing tumor samples and patient data to uncover potential targets for innovative therapies.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with Non-Hodgkin lymphoma, especially those who are also HIV-positive.
Not a fit: Patients with Non-Hodgkin lymphoma who are not infected with HIV may not benefit directly from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for patients with Non-Hodgkin lymphoma, particularly those who are HIV-positive.
How similar studies have performed: Previous research has shown promising results in targeting EBV-associated malignancies, indicating that this approach may lead to significant advancements in treatment.
Where this research is happening
Chapel Hill, United States
- Univ of North Carolina Chapel Hill — Chapel Hill, United States (Active)
Researchers
- Principal investigator: Damania, Blossom a — Univ of North Carolina Chapel Hill
- Study coordinator: Damania, Blossom a
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.