New treatments for melanoma and skin cancer

Melanoma and Skin Cancer Program SPORE

NIH-funded research University of Pittsburgh at Pittsburgh · NIH-10926821

This study is looking for new and better ways to treat melanoma and skin cancer for patients who haven't had success with current treatments, including trying out a special device that delivers chemotherapy through tiny needles.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of Pittsburgh at Pittsburgh NIH-funded
Lab location1 site (Pittsburgh, United States)
Project IDNIH-10926821 on NIH RePORTER

What this research studies

This research focuses on developing innovative therapies for melanoma and cutaneous squamous cell carcinoma (cSCC), which are among the most common cancers in the U.S. The program aims to create new combinatorial immunotherapy trials that could improve treatment outcomes for patients who have not responded to existing therapies. It includes evaluating the effectiveness of new drugs and treatment methods, such as a microneedle device for delivering chemotherapy. Patients will be involved in clinical trials that assess the safety and efficacy of these novel approaches.

Who could benefit from this research

Good fit: Ideal candidates for participation are patients with advanced melanoma or cSCC who have not previously received immunotherapy.

Not a fit: Patients with early-stage melanoma or cSCC who are not eligible for clinical trials may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective and safer treatment options for patients with melanoma and skin cancer.

How similar studies have performed: Previous research has shown promise in using combinatorial immunotherapy approaches for melanoma, indicating potential for success in this novel application.

Where this research is happening

Pittsburgh, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Cancer BiologyCancer CenterCancer Patient
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.