New treatments for lymphatic problems caused by obesity and diabetes
Official title: Novel therapies for obesity- or diabetes-related lymphatic dysfunction
Funded at Larix Bioscience, LLC · NIH-10602589 · Data updated 2026-11-12
This study is looking for new treatments to help people with lymphatic dysfunction caused by obesity and diabetes, and it aims to find out how these conditions affect lymphatic health, so patients can try out these new therapies and see if they help improve their symptoms.
Quick facts
| Grant type | Sbir 1 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Larix Bioscience, LLC NIH-funded |
| Lab location | 1 site (Sunnyvale, United States) |
| Project start | September 1, 2023 |
| Project end | August 31, 2025 |
| Funding year | 2023 |
| Award (this year) | $245,728 |
| NIH project number | 1R43HL154880-01A1 |
| Project ID | NIH-10602589 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adults who are morbidly obese or have diabetes and are experiencing symptoms of lymphatic dysfunction.
✕Less likely to help
Patients who do not have obesity or diabetes, or those without symptoms of lymphatic dysfunction, may not benefit from this research.
What this research studies
This research focuses on developing novel therapies to address lymphatic dysfunction (LD), a condition that can arise from obesity and diabetes. The study aims to understand the underlying mechanisms of LD and explore new pharmaceutical preparations that could alleviate symptoms and improve patient outcomes. By investigating the relationship between endothelial dysfunction and lymphatic health, the research seeks to provide effective solutions for those suffering from this often-overlooked complication. Patients may be involved in trials testing these new therapies to see how well they work in reducing the effects of LD.
Why it matters
Potential benefit: If successful, this research could lead to effective treatments that significantly improve the quality of life for patients suffering from lymphatic dysfunction related to obesity and diabetes.
How similar studies have gone: While lymphatic dysfunction has been recognized as a significant issue, this research represents a novel approach to developing targeted therapies, as similar studies have not extensively explored this area.
Where this research is happening
-
Larix Bioscience, LLC
Sunnyvale, United States Active
Researchers
- Principal investigator: Hu, Mickey — Larix Bioscience, LLC
- Study coordinator: Hu, Mickey
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.