New treatments for lung problems in premature infants

Therapeutic Strategies for the Management of Bronchopulmonary Dysplasia-Associated Pulmonary Hypertension

['FUNDING_OTHER'] · YALE UNIVERSITY · NIH-11239367

This study is looking for new ways to help premature babies who have bronchopulmonary dysplasia and high blood pressure in their lungs, with the goal of making them healthier and reducing serious health risks.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorYALE UNIVERSITY (nih funded)
Locations1 site (NEW HAVEN, UNITED STATES)
Trial IDNIH-11239367 on ClinicalTrials.gov

What this research studies

This research focuses on developing new therapeutic strategies to manage bronchopulmonary dysplasia-associated pulmonary hypertension (BPD-PH) in infants. Dr. Samuel Gentle aims to reduce the high rates of morbidity and mortality associated with this condition, which affects many premature infants. The research will involve innovative translational and interventional approaches, potentially leading to multi-center clinical trials that could improve outcomes for these vulnerable patients. The project is supported by a strong mentorship team with extensive experience in related research.

Who could benefit from this research

Good fit: Ideal candidates for this research are premature infants diagnosed with bronchopulmonary dysplasia and associated pulmonary hypertension.

Not a fit: Patients who are not premature or do not have bronchopulmonary dysplasia-associated pulmonary hypertension may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly improve survival rates and quality of life for infants suffering from BPD-PH.

How similar studies have performed: While the specific approaches in this research may be novel, there is a history of successful interventions in similar conditions that suggest potential for positive outcomes.

Where this research is happening

NEW HAVEN, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.