New treatments for healing diabetic foot ulcers

COATs: Collagen-mimetic peptide and therapeutic gene-modified collagens for cell-mediated healing of diabetic foot ulcers

NIH-funded research University of Delaware · NIH-11097243

This study is exploring new treatments for diabetic foot ulcers to help them heal better and faster, using special materials that encourage your body to produce the healing factors it needs, so you can recover more effectively.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Delaware NIH-funded
Lab location1 site (Newark, UNITED STATES)
Project IDNIH-11097243 on NIH RePORTER

What this research studies

This research focuses on developing innovative therapies for diabetic foot ulcers, which are a significant health issue leading to many amputations. The approach involves using collagen-mimetic peptides and gene-modified collagens to enhance the healing process by stimulating the body's own cells to produce necessary growth factors. By creating a supportive environment for healing, the research aims to improve the effectiveness of wound dressings and promote faster recovery. Patients may benefit from a new treatment that addresses the underlying issues preventing proper healing.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals suffering from diabetic foot ulcers who have not responded well to standard treatments.

Not a fit: Patients with foot ulcers caused by non-diabetic conditions may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective treatments for diabetic foot ulcers, reducing the need for amputations and improving patient outcomes.

How similar studies have performed: Previous research has shown promise in using gene therapy and biomaterials for wound healing, indicating that this approach could be effective.

Where this research is happening

Newark, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.