New treatments for chronic pain from mild brain injuries
Novel treatments of chronic pain due to repetitive mild traumatic brain injury
['FUNDING_OTHER'] · RLR VA MEDICAL CENTER · NIH-10932964
This study is looking at how mild concussions, which many older veterans experience, can lead to long-lasting pain and inflammation in the brain, and it hopes to find new ways to help those dealing with chronic pain from these injuries.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | RLR VA MEDICAL CENTER (nih funded) |
| Locations | 1 site (INDIANAPOLIS, UNITED STATES) |
| Trial ID | NIH-10932964 on ClinicalTrials.gov |
What this research studies
This research investigates how mild concussive events, often experienced by older veterans, lead to chronic pain and neuroinflammation. By using a special type of mouse that can show changes in brain inflammation, the researchers aim to understand the processes that contribute to long-term pain after such injuries. The study will explore the role of specific proteins involved in inflammation and how they affect pain perception over time. This approach may help identify new treatment strategies for those suffering from chronic pain due to mild traumatic brain injuries.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults, particularly veterans, who have experienced mild concussive events and suffer from chronic pain.
Not a fit: Patients who have not experienced mild traumatic brain injuries or do not suffer from chronic pain related to such injuries may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that alleviate chronic pain for patients with a history of mild brain injuries.
How similar studies have performed: Previous research has shown promising results in understanding neuroinflammation and its role in chronic pain, suggesting that this approach may yield valuable insights.
Where this research is happening
INDIANAPOLIS, UNITED STATES
- RLR VA MEDICAL CENTER — INDIANAPOLIS, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: WHITE, FLETCHER A — RLR VA MEDICAL CENTER
- Study coordinator: WHITE, FLETCHER A
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: axon injury, axonal injury