New treatments for childhood obesity using dual hormone therapies
Official title: Efficacy of Novel Melanocortin and Gut-peptide Dual Agonists for Childhood Obesity Treatment
Funded at Seattle Children's Hospital · NIH-11056615 · Data updated 2026-11-12
This study is looking at new ways to help kids and teens with obesity by creating special treatments that can help them feel less hungry and lose weight, all while being easier on their bodies than current options.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Seattle Children's Hospital NIH-funded |
| Lab location | 1 site (Seattle, United States) |
| Project start | September 19, 2024 |
| Project end | August 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $531,174 |
| NIH project number | 1R21HD115119-01A1 |
| Project ID | NIH-11056615 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are children and adolescents struggling with obesity who may benefit from new treatment options.
✕Less likely to help
Patients who are not experiencing obesity or those with conditions that contraindicate the use of hormonal therapies may not benefit from this research.
What this research studies
This research investigates innovative treatments for childhood obesity by developing dual agonists that target both melanocortin and gut peptides. These therapies aim to suppress appetite and promote weight loss while minimizing side effects commonly associated with existing treatments. The approach focuses on enhancing energy expenditure and improving compliance among children and adolescents who struggle with obesity. By combining multiple mechanisms, the research seeks to provide a more effective and tolerable solution for young patients.
Why it matters
Potential benefit: If successful, this research could lead to more effective and safer weight loss treatments for children and adolescents with obesity.
How similar studies have gone: Previous research has shown promise in using hormonal therapies for obesity treatment, indicating that this approach may lead to significant advancements.
Where this research is happening
-
Seattle Children's Hospital
Seattle, United States Active
Researchers
- Principal investigator: Roth, Christian Ludwig — Seattle Children's Hospital
- Study coordinator: Roth, Christian Ludwig
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.