New Treatments for Childhood Neuroblastoma
NCI Pediatric In Vivo Testing Program: Neuroblastoma
This research aims to find better, personalized treatments for children with a serious type of cancer called neuroblastoma.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Children's Hosp of Philadelphia NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project ID | NIH-11109481 on NIH RePORTER |
What this research studies
Children with widespread neuroblastoma often face significant challenges with current treatments, so this project focuses on finding new solutions. Researchers are using models created from actual patient tumors, grown in mice, to test many different anti-cancer medicines. The goal is to understand the unique genetic features of each patient's neuroblastoma and use this information to develop targeted therapies. This approach helps identify the most promising new drugs that could eventually be used in clinical trials for children.
Who could benefit from this research
Good fit: This research focuses on understanding and treating neuroblastoma, particularly in children with widespread disease.
Not a fit: Patients without neuroblastoma would not directly benefit from this specific research.
Why it matters
Potential benefit: If successful, this work could lead to more effective and personalized treatments for children with neuroblastoma, improving their chances of cure.
How similar studies have performed: This program builds upon previous successful pediatric preclinical testing efforts, indicating a foundation of established methods.
Where this research is happening
Philadelphia, United States
- Children's Hosp of Philadelphia — Philadelphia, United States (Active)
Researchers
- Principal investigator: Mosse, Yael P — Children's Hosp of Philadelphia
- Study coordinator: Mosse, Yael P
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.