New treatments for bacterial eye infections
Official title: Chromosome Packing Inhibitors for the Treatment of Eye Infections
Funded at University of Oklahoma · NIH-10975696 · Data updated 2026-11-12
This study is looking for new ways to treat bacterial eye infections, especially for people who have had surgery or use contact lenses, by testing a special type of medicine that could help fight stubborn bacteria and protect your vision.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Oklahoma NIH-funded |
| Lab location | 1 site (Norman, United States) |
| Project start | September 1, 2024 |
| Project end | August 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $201,825 |
| NIH project number | 1R21EY036599-01 |
| Project ID | NIH-10975696 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals who have experienced or are at risk for bacterial eye infections, particularly those related to contact lens use or eye surgeries.
✕Less likely to help
Patients with non-bacterial eye infections or those who do not wear contact lenses or have not undergone eye surgery may not benefit from this research.
What this research studies
This research focuses on developing new antibacterial treatments specifically for bacterial eye infections, which can occur after surgeries or from contact lens use. The approach involves testing chromosome packing inhibitors, which target the organization and segregation of bacterial chromosomes, to see if they can effectively combat resistant strains of bacteria like Pseudomonas aeruginosa. By understanding how these inhibitors affect bacterial behavior during eye infections, the research aims to find a novel treatment that could prevent vision loss.
Why it matters
Potential benefit: If successful, this research could lead to effective new treatments for bacterial eye infections, reducing the risk of vision loss.
How similar studies have gone: Other research has shown promise in targeting bacterial chromosome organization as a novel approach to treating infections, indicating potential for success in this area.
Where this research is happening
-
University of Oklahoma
Norman, United States Active
Researchers
- Principal investigator: Rybenkov, Valentin V — University of Oklahoma
- Study coordinator: Rybenkov, Valentin V
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.