New treatment to help heal mouth injuries faster.
Official title: Innovative oral regenerative therapy leveraging immunoregenerative mechanisms.
Funded at Oridivus LLC · NIH-11259125 · Data updated 2026-11-12
This study is looking at a new way to help your mouth heal better after surgeries like fixing a cleft palate or removing wisdom teeth by using a special treatment that encourages your body's immune system to work more effectively at the healing site.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Oridivus LLC NIH-funded |
| Lab location | 1 site (Decatur, United States) |
| Project start | May 12, 2025 |
| Project end | July 15, 2025 |
| Funding year | 2025 |
| Award (this year) | $55,000 |
| NIH project number | 3R41DE033573-01S1 |
| Project ID | NIH-11259125 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals who have experienced oral injuries due to procedures like cleft palate repair or wisdom teeth extraction.
✕Less likely to help
Patients with oral injuries unrelated to the conditions being studied may not benefit from this research.
What this research studies
This research investigates a novel approach to enhance healing in the oral cavity following injuries such as cleft palate repair or wisdom teeth removal. It utilizes a murine model to explore the effects of an immunomodulatory treatment that delivers a biolipid called FTY720, which aims to attract specific immune cells to the wound site to promote a healthier healing environment. By focusing on the body's natural regenerative processes, the study seeks to improve outcomes for patients suffering from complications related to oral wounds. The ultimate goal is to develop a safe and effective therapy that can be used in clinical settings.
Why it matters
Potential benefit: If successful, this research could significantly reduce complications and improve healing times for patients with oral injuries.
How similar studies have gone: While similar immunomodulatory approaches have shown promise in other areas of medicine, this specific application in oral wound healing is relatively novel.
Where this research is happening
-
Oridivus LLC
Decatur, United States Active
Researchers
- Principal investigator: Goudy, Steven L — Oridivus LLC
- Study coordinator: Goudy, Steven L
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.