New treatment to help heal mouth injuries faster.
Official title: Innovative oral regenerative therapy leveraging immunoregenerative mechanisms.
Funded at Oridivus LLC · NIH-10821571 · Data updated 2026-11-12
This study is looking at a new way to help heal mouth wounds, like those from surgeries for cleft palates or wisdom teeth removal, by using a special substance to attract healing cells, and it's being tested in mice to find better treatments for people dealing with these kinds of injuries.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Oridivus LLC NIH-funded |
| Lab location | 1 site (Decatur, United States) |
| Project start | July 16, 2024 |
| Project end | December 15, 2025 |
| Funding year | 2024 |
| Award (this year) | $306,499 |
| NIH project number | 1R41DE033573-01 |
| Project ID | NIH-10821571 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include children and adults who have experienced oral injuries from surgeries or trauma.
✕Less likely to help
Patients with chronic oral conditions unrelated to surgical wounds may not benefit from this research.
What this research studies
This research focuses on improving the healing process of oral wounds, which can occur due to surgeries like cleft palate repair or wisdom teeth removal. It uses a special approach that involves delivering a biolipid called FTY720 to attract specific immune cells that promote healing. By testing this method in a mouse model, the researchers aim to create a more effective treatment for patients suffering from complications related to oral injuries. The goal is to enhance recovery and reduce the need for additional surgeries.
Why it matters
Potential benefit: If successful, this research could lead to faster and more effective healing of oral wounds, reducing pain and the need for further surgeries.
How similar studies have gone: While the approach of using immunomodulatory therapies is promising, this specific application in oral wound healing is relatively novel and has not been extensively tested in humans.
Where this research is happening
-
Oridivus LLC
Decatur, United States Active
Researchers
- Principal investigator: Goudy, Steven L — Oridivus LLC
- Study coordinator: Goudy, Steven L
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.