New treatment to fight infections in chronic wounds
Antimicrobial Treatment to Combat Wound Biofilm
['FUNDING_SBIR_2'] · ALLVIVO VASCULAR, INC. · NIH-11089568
This study is testing a new gel called Gatekeeper™ that helps heal stubborn wounds by fighting off bacteria that can cause infections, making it a great option for anyone struggling with chronic wounds.
Quick facts
| Phase | ['FUNDING_SBIR_2'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | ALLVIVO VASCULAR, INC. (nih funded) |
| Locations | 1 site (LAKE FOREST, UNITED STATES) |
| Trial ID | NIH-11089568 on ClinicalTrials.gov |
What this research studies
This research focuses on developing a novel antimicrobial treatment for chronic wounds, which often fail to heal due to the presence of biofilms that protect bacteria. The project aims to create a product called Gatekeeper™, which is a biocompatible and biodegradable hydrogel that effectively targets and eliminates bacteria in these biofilms. By maintaining a moist environment and ensuring close contact with the wound, this treatment seeks to enhance healing and prevent further infections. The efficacy of Gatekeeper™ has been demonstrated in various laboratory and animal models.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals suffering from chronic wounds that are resistant to standard treatments.
Not a fit: Patients with acute wounds or those not affected by biofilm-related infections may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly improve healing outcomes for patients with chronic wounds, reducing the risk of serious infections and amputations.
How similar studies have performed: Previous research has shown promise in using antimicrobial peptides for treating biofilm-related infections, indicating potential success for this novel approach.
Where this research is happening
LAKE FOREST, UNITED STATES
- ALLVIVO VASCULAR, INC. — LAKE FOREST, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: NEFF, JENNIFER ANN — ALLVIVO VASCULAR, INC.
- Study coordinator: NEFF, JENNIFER ANN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.