New treatment targeting the tumor environment in inflammatory breast cancer
Development of a novel therapy targeting the tumor microenvironment in inflammatory breast cancer
This study is looking at inflammatory breast cancer, especially how it affects Native Hawaiian and Pacific Islander women, to find out why some groups have different treatment results, and it hopes to discover new ways to improve therapies by examining tumor samples.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Hawaii at Manoa NIH-funded |
| Lab location | 1 site (Honolulu, United States) |
| Project ID | NIH-11014837 on NIH RePORTER |
What this research studies
This research focuses on inflammatory breast cancer (IBC), a particularly aggressive form of breast cancer that disproportionately affects Native Hawaiian and Pacific Islander women. The project aims to understand the biological mechanisms behind the disparities in treatment outcomes among different racial and ethnic groups. By analyzing tumor samples from IBC patients, the researchers will identify molecular targets that could lead to improved therapies. The approach includes advanced techniques like RNA sequencing to characterize the tumor microenvironment and its impact on cancer progression.
Who could benefit from this research
Good fit: Ideal candidates for this research include women diagnosed with inflammatory breast cancer, especially those who are Native Hawaiian, Pacific Islander, or Asian American.
Not a fit: Patients with other types of breast cancer or those who do not belong to the targeted racial/ethnic groups may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for inflammatory breast cancer, particularly for underrepresented populations.
How similar studies have performed: Previous research has shown promise in targeting the tumor microenvironment in other cancer types, suggesting potential for success in this novel approach for inflammatory breast cancer.
Where this research is happening
Honolulu, United States
- University of Hawaii at Manoa — Honolulu, United States (Active)
Researchers
- Principal investigator: Ueno, Naoto T. — University of Hawaii at Manoa
- Study coordinator: Ueno, Naoto T.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.