New treatment for painful nerve damage caused by chemotherapy in young cancer patients

Innovative Treatment of Chemotherapy-Induced Painful Peripheral Neuropathy in Adolescents and Young Adults with Cancer: A two arm pilot study

NIH-funded research University of Tx Md Anderson Can Ctr · NIH-10560600

This study is looking at a new, gentle treatment called scrambler therapy to help young people with cancer who are dealing with painful nerve issues from chemotherapy, and it aims to see if this method can make them feel better without the harsh side effects of regular medications.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionUniversity of Tx Md Anderson Can Ctr NIH-funded
Lab location1 site (Houston, United States)
Project IDNIH-10560600 on NIH RePORTER

What this research studies

This research investigates a novel noninvasive technique called scrambler therapy to treat chemotherapy-induced painful peripheral neuropathy (CIPN) in adolescents and young adults with cancer. The study compares this new approach to standard treatments, aiming to improve the quality of life for patients suffering from debilitating nerve pain. Participants will receive scrambler therapy sessions, which may help alleviate their symptoms without the severe side effects associated with traditional medications. The research focuses on understanding the effectiveness of this technique specifically in younger patients, who have been underrepresented in previous studies.

Who could benefit from this research

Good fit: Ideal candidates for this research are adolescents and young adults diagnosed with cancer who are experiencing chemotherapy-induced peripheral neuropathy.

Not a fit: Patients who are not currently undergoing chemotherapy or those with other underlying conditions causing neuropathy may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could provide a safer and more effective treatment option for young cancer patients suffering from nerve pain due to chemotherapy.

How similar studies have performed: While scrambler therapy has shown promise in adult populations, its application in adolescents and young adults with CIPN is relatively novel and has not been extensively tested.

Where this research is happening

Houston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Malignant childhood cancercancer in a childcancer in childrenchild with cancerchildren with cancer
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.