New treatment for nicotine addiction using e-vape technology.

Revolutionizing Nicotine Vaping and Electronic Nicotine Delivery Systems Addiction Treatment through Innovative E-Vape Administration of Cytisine to Enhance Patient Adherence and Treatment Completion.

['FUNDING_SBIR_1'] · SPACERX LLC · NIH-11008626

This study is testing a new way to help people quit smoking or vaping by using a medication called cytisine in e-vape devices, making it easier for those who have tried to quit before to stick with their treatment.

Quick facts

Phase['FUNDING_SBIR_1']
Study typeNih_funding
SexAll
SponsorSPACERX LLC (nih funded)
Locations1 site (RESTON, UNITED STATES)
Trial IDNIH-11008626 on ClinicalTrials.gov

What this research studies

This research focuses on developing a novel treatment for nicotine addiction by using cytisine, a smoking cessation drug, administered through e-vape devices. The approach aims to enhance patient adherence and treatment completion by allowing individuals to self-administer the medication in a familiar format. The study targets those who have struggled with quitting smoking or vaping, particularly those who have made multiple unsuccessful attempts. By addressing both the physical and behavioral aspects of nicotine addiction, this research seeks to provide a more effective solution for cessation.

Who could benefit from this research

Good fit: Ideal candidates for this research are adults and adolescents who are dependent on nicotine and have previously attempted to quit without success.

Not a fit: Patients who are not currently using nicotine products or those who have successfully quit smoking or vaping may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly improve the success rates of individuals trying to quit nicotine by providing a more accessible and effective treatment option.

How similar studies have performed: While the use of cytisine for smoking cessation has been explored, this specific approach using e-vape technology is innovative and has not been widely tested.

Where this research is happening

RESTON, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.