New treatment approach for improving blood flow in patients with peripheral artery disease
Bioengineered Composite for the Treatment of Peripheral Arterial Disease
This study is working on a new injectable treatment made from special materials to help improve blood flow and blood vessel growth for people with peripheral artery disease (PAD), aiming to make existing therapies work better or even serve as a standalone option.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Washington University NIH-funded |
| Lab location | 1 site (Saint Louis, United States) |
| Project ID | NIH-11054610 on NIH RePORTER |
What this research studies
This research focuses on developing a bioengineered composite material aimed at treating peripheral artery disease (PAD), which affects millions of people. The approach involves creating a specialized injectable material that can enhance the effectiveness of existing therapies or serve as a standalone treatment. The researchers will optimize the material's properties to ensure it can withstand the dynamic environment of muscle tissue while promoting blood vessel growth and improving blood flow. By using advanced biomaterials, the study aims to provide a more effective solution for managing the symptoms of PAD.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with peripheral artery disease who experience symptoms such as leg pain or cramping during physical activity.
Not a fit: Patients with advanced stages of peripheral artery disease or those who have other severe comorbidities may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment options that enhance blood flow and reduce symptoms for patients with peripheral artery disease.
How similar studies have performed: Previous research has shown promising results using biomaterials in similar contexts, indicating potential for success in this novel approach.
Where this research is happening
Saint Louis, United States
- Washington University — Saint Louis, United States (Active)
Researchers
- Principal investigator: Li, Xiaowei — Washington University
- Study coordinator: Li, Xiaowei
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.